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2016 
  

16-8: Visible light-induced monofluoromethylenation of heteroarenes with ethyl bromofluoroacetate

  Wei Yu, Xiu-Hua Xu and Feng-Ling Qing* 

  New J. Chem. 2016, 40, 6564-6567. DOI: 10.1039/C6NJ00281A

16-7: Photoredox-catalyzed bromodifluoromethylation of alkenes with difluoromethyltriphenylphosphonium bromide

  Qing-Yu Lin, Yang Ran, Xiu-Hua Xu and Feng-Ling Qing* 

  Org. Lett. 2016, 18, 2419-2422. DOI: 10.1021/acs.orglett.6b00935

16-6: Bromodifluoromethylation of heteroaromatics with sodium bromodifluoromethanesulfinate

  Jin Zhang, Xiu-Hua Xu and Feng-Ling Qing* 

  Tetrahedron Lett. 2016, 57, 2462-2464. DOI: 10.1016/j.tetlet.2016.04.095

16-5: Copper-mediated trifluoromethylation of diaryliodonium salts with difluoromethyltriflate 

  Jing-Yun Yang, Xiu-Hua Xu and Feng-Ling Qing* 

  J. Fluorine Chem. 2016, 18645-51DOI: 10.1016/j.jfluchem.2016.04.008

16-4: Visible Light-Induced Oxydifluoromethylation of Styrenes with Difluoromethyltriphenylphosphonium Bromide

  Yang Ran, Qing-Yu Lin, Xiu-Hua Xu and Feng-Ling Qing* 

  J. Org. Chem. 2016, 81, 7001-7007DOI: 10.1021/acs.joc.6b00234

 

16-3: Synthesis of α-trifluoromethyl-β-keto phosphonates by eletrophilic trifluoromethylation with togni reagent

  Wen-Zhi Fu, Yangen Huang, Xiu-Hua Xu and Feng-Ling Qing* 

  Synth. Commun. 2016, 46415-420DOI: 10.1080/00397911.2016.1139724 

16-2: Visible-Light Induced Hydrodifluoromethylation of Alkenes with Bromodifluoromethylphosphonium Bromide

  Qing-Yu Lin, Xiu-Hua Xu, Ke Zhang and Feng-Ling Qing* 

  Angew. Chem. Int. Ed. 2016, 551479-1483DOI: 10.1002/anie.201509282

 

16-1: Iron-mediated chlorotrifluoromethylation of alkenes with sodium trifluoromethanesulfinate

   Bin Yang, Xiu-Hua Xu and Feng-Ling Qing*  

   Chin. J. Chem. 2016, 34, 465-468. DOI: 10.1002/cjoc.201500641

 
 
2015 

15-13: Copper-mediated trifluoromethylation of diaryliodonium salts with TMSCF3 at room temperature

   Jing-Yun Yang, Xiu-Hua Xu and Feng-Ling Qing*  

   J. Fluorine Chem. 2015180175-180. DOI: 10.1016/j.fluchem.2015.09.015

15-12: Silver-Mediated Oxidative Trifluoromethylation of Alcohols to Alkyl Trifluoromethyl Ethers

   Jian-Bo Liu, Xiu-Hua Xu and Feng-Ling Qing* 

   Org. Lett. 2015, 17, 5048-5051. DOI: 10.1021/acs.orglett.5b02522

15-11: Copper-mediated oxidative trifluoromethylthiolation of quinones

   Chao Li, Ke Zhang, Xiu-Hua Xu and Feng-Ling Qing*  

   Tetrahedron Lett. 201556, 6273-6275. DOI: 10.1016/j.tetlet.2015.09.117

15-10: Silver-Mediated Oxidative Trifluoromethylation of Phenols: The Direct Synthesis of Aryl Trifluoromethyl Ethers

   Jian-Bo Liu, Chao Chen, Lingling Chu etc. and Feng-Ling Qing* 

   Angew. Chem. Int. Ed. 2015, 54, 11839-11942. (VIP) DOI: 10.1002/anie.201506329.

15-9: Visible light-induced selective hydrobromodifluoromethylation of alkenes with dibromodifluoromethane

   Qing-Yu Lin, Xiu-Hua Xu and Feng-Ling Qing*  

   Org. Biomol. Chem. 2015138740-8749. DOI: 10.1039/C5OB01302J

15-8: Copper-Promoted Trifluoromethanesulfonylation and Trifluoromethylation of Arenediazonium Tetrafluoroborates with NaSO2CF3

   Ke Zhang, Xiu-Hua Xu and Feng-Ling Qing*  

   J. Org. Chem. 2015, 80, 7658-7665. DOI: 10.1021/acs.joc.5b01295

15-7: Copper-mediated oxidative difluoromethylation of terminal alkynes with TMSCF2

   Sheng-Qing Zhu, Xiu-Hua Xu and Feng-Ling Qing*  

   Org. Chem. Front. 2015, 21022-1025. DOI: 10.1039/C5QO00186B

15-6: Recent Developments in the Fluorofunctionalization of Alkenes

   Xiu-Hua Xu and Feng-Ling Qing*  

   Curr. Org. Chem. 2015, 19, 1566-1578. DOI: 10.2174/1385272819666150429230707

15-5: Silver-Mediated Oxidative Fluorotrifluoromethylation of Unactivated Alkenes

   Wei Yu, Xiu-Hua Xu and Feng-Ling Qing* 

   Adv. Synth. Catal. 2015, 357, 2039-2044. DOI: 10.1002/adsc.201500027

15-4: Copper-Mediated Radical 1,2-Bis(trifluoromethylation) of Alkenes with Sodium Trifluoromethanesulfinate

   Bin Yang, Xiu-Hua Xu and Feng-Ling Qing* 

   Org. Lett. 2015, 17, 1906-1909. DOI: 10.1021/acs.orglett.5b00601

  

15-3: Recent Advances of Direct Trifluoromethylthiolation

   Ke Zhang, Xiu-Hua Xu and Feng-Ling Qing*  

   Chin. J. Org. Chem. 2015, 35, 556-569. DOI: 10.6023/cjoc201501017

15-2: Direct Dehydroxytrifluoromethylthiolation of Alcohols Using Silver(I) Trifluoromethanethiolate and Tetra-n-butylammonium Iodide

   Jian-Bo Liu, Xiu-Hua Xu, Zeng-Hao Chen and Feng-Ling Qing* 

   Angew. Chem. Int. Ed. 2015, 54, 897-900. DOI: 10.1002/anie.201409983

  

15-1: Regio- and Diastereoselective Vinylogous Mannich Addition of 3-Alkenyl-2-oxindoles to α-Fluoroalkyl Aldimines

   Yingle Liu, Yi Yang, Hangen Huang, Xiu-Hua Xu and Feng-Ling Qing*  

   Synlett 2015, 26, 67-72. DOI: 10.1055/s-0034-1379600

 

2014
 
14-9: Oxidative Trifluoromethylation and Trifluoromethylthiolation Reactions Using (Trifluoromethyl)trimethylsilane as a Nucleophilic CF3 Source

   Lingling Chu and Feng-Ling Qing* 

   Acc. Chem. Res. 2014, 47, 1513-1522. DOI: dx.doi.org/10.1021/ar4003202

14-8: Chemo‑, Regio‑, and Stereoselective Trifluoromethylation of Styrenes via Visible Light-Driven Single-Electron Transfer (SET) and Triplet−Triplet Energy Transfer (TTET) Processes

   Qing-Yu Lin, Xiu-Hua Xu and Feng-Ling Qing* 

   J. Org. Chem. 2014, 79, 10434-10446. DOI: dx.doi.org/10.1021/jo502040t

 

14-7: Copper-mediated oxidative trifluoromethylthiolation of unactivated terminal alkenes

   Ke Zhang, Jian-Bo Liu and Feng-Ling Qing* 

   Chem. Commun. 2014, 50, 10147-10150. DOI: 10.1039/c4cc07062c

 

14-6: Trifluoromethylated nucleic acid analogues capable of self-assembly through hydrophobic interactions

   RuoWen Wang, Chunming Wang etc., Feng-Ling Qing* and Weihong Tan*

   Chem. Sci. 20145, 4076-4081. DOI: 10.1039/c4sc01162g

14-5: Copper-mediated difluoromethylation of electron-poor aryl iodides at room temperature 

   Xue-Liang Jiang, Zeng-Hao Chen, Xiu-Hua Xu* and Feng-Ling Qing*

   Org. Chem. Front. 20141, 774-776. DOI: 10.1039/c4qo00153b

14-4: Design and concise synthesis of gem-difluoromethylenated analogue of 7-epi-castanospermine

   Xin-Yi Jiang, Xiu-Hua Xu and Feng-Ling Qing*

   Chin. Chem. Lett. 201425, 1115-1120. DOI: 10.1016/j.cclet.2014.04.018

14-3: Copper-Catalyzed Direct Trifluoromethylthiolation of Benzylic C−H Bonds via Nondirected Oxidative C(sp3)−H Activation

   Chao Chen, Xiu-Hua Xu, Bin Yang and Feng-Ling Qing*

   Org. Lett. 2014, 16, 3372-3375. DOI: 10.1021/ol501400u

 

14-2: Automated Modular Synthesis of Aptamer–Drug Conjugates for Targeted Drug Delivery 

   RuoWen Wang, Guizhi Zhu, Lei Mei etc., Feng-Ling Qing, and Weihong Tan*

   J. Am. Chem. Soc. 2014, 136, 2731-2734. DOI: dx.doi.org/10.1021/ja4117395 

14-1: Oxidative Trifluoromethylthiolation of Terminal Alkynes with AgSCF3A Convenient Approach to Alkynyl Trifluoromethyl Sulfides

   Sheng-Qing Zhu, Xiu-Hua Xu* and Feng-Ling Qing*

   Eur. J. Org. Chem. 2014, 4453-4456. DOI: 10.1002/ejoc.201402533

   

2013 

13-11: Copper-Catalyzed Three-Component Oxytrifluoromethylation of Alkenes with Sodium Trifluoromethanesulfinate and Hydroxamic Acid

   Xin-Yi Jiang and Feng-Ling Qing*

   Angew. Chem. Int. Ed. 201352, 14177-14180. DOI: 10.1002/anie.201307595

 

13-10: 4-CF3-ezetimibe analogs: design, synthesis, and biological evaluation of cholesterol absorption inhibitions

   Yingle Liu, Jun-Ling Chen, Gai-Hong Wang etc. and Feng-Ling Qing*

   Tetrahedron Lett. 201354, 5541-5543. DOI: 10.1016/j.tetlet.2013.08.027

13-9: Palladium-Catalyzed Anti-Markovnikov Hydroalkylation of Homoallylic Alcohols Bearing β‑Fluorines

   Xiaowei Lin and Feng-Ling Qing*

   Org. Lett. 2013, 15, 4478-4481. DOI: 10.1021/ol402032a

 

13-8: Lewis acid-catalyzed regioselective synthesis of chiral α-fluoroalkyl amines via asymmetric addition of silyl dienolates to fluorinated sulfinylimines

   Yingle Liu, Jiawang Liu, Yangen Huang and Feng-Ling Qing*

   Chem. Commun. 201349, 7492-7494. DOI: 10.1039/c3cc43741h

 

13-7: Direct Introduction of Ethoxycarbonyldifluoromethyl-Group to Heteroarenes with Ethyl Bromodifluoroacetate via Visible-Light Photocatalysis

   Qingyu Lin, Lingling Chu and Feng-Ling Qing*

   Chin. J. Chem. 2013, 31, 885-891. DOI: 10.1002/cjoc.201300411

13-6: Asymmetric synthesis of trifluoromethylated aziridines from CF3-substituted N-tert-butanesulfinyl ketimines

   Yanmei Yang, Yangen Huang and Feng-Ling Qing*

   Tetrahedron Lett. 201354, 3826-3830. DOI: 10.1016/j.tetlet.2013.05.048

13-5: Copper-mediated oxidative difluoromethylenation of aryl boronic acids with α-silyldifluoromethylphosphonates: a new method for aryldifluorophosphonates

   Xueliang Jiang, Lingling Chu and Feng-Ling Qing*

   New J. Chem. 2013, 37, 1736-1741. DOI: 10.1039/c3nj00044c

13-4: Electrophilic Trifluoromethylthiolation of Allylsilaneswith Trifluoromethanesulfanamide

   Jianbo Liu, Lingling Chu and Feng-Ling Qing*

   Org. Lett. 2013, 15, 894-897. DOI: 10.1021/ol400032g

 

13-3: Cu-Mediated trifluoromethylation of benzyl, allyl and propargyl methanesulfonates with TMSCF3

   Xueliang Jiang and Feng-Ling Qing*

   Beilstein J. Org. Chem. 20139, 2862-2865. DOI: 10.3762/bjoc.9.322

13-2: Silver-Catalyzed Hydrotrifluoromethylation of Unactivated Alkenes with CF3SiMe3

   Xinyue Wu, Lingling Chu and Feng-Ling Qing*

   Angew. Chem. Int. Ed. 2013, 52, 2198-2202. DOI: 10.1002/anie.201208971

 

13-1: PhI(OAc)2-mediated oxidative trifluoromethylation of arenes with CF3SiMe3 under metal-free conditions

   Xinyue Wu, Lingling Chu and Feng-Ling Qing*

   Tetrahedron Lett. 2013, 54, 249-251. DOI: 10.1016/j.tetlet.2012.11.011

 

2012 

12-17: Copper-Catalyzed Oxidative Trifluoromethylthiolation of Aryl Boronic Acids with TMSCF3 and Elemental Sulfur

   Chao Chen, Yan Xie, Lingling Chu etc. and Feng-Ling Qing*

   Angew. Chem. Int. Ed. 201251, 2492-2495. DOI: 10.1002/anie.201108663

 

12-16: An Improved Copper-Mediated Oxidative Trifluoromethylation of Terminal Alkynes

   Ke Zhang, Xiao-Long Qiu, Yangen Huang and Feng-Ling Qing*

   Eur. J. Org. Chem. 2012, 58-61. DOI: 10.1002/ejoc.201101550

12-15: Copper-Catalyzed Direct C−H Oxidative Trifluoromethylation of Heteroarenes

   Lingling Chu and Feng-Ling Qing*

   J. Am. Chem. Soc. 2012, 134, 1298-1304. DOI: 10.1021/ja209992w

 

12-14: Metal-Free Oxidative Trifluoromethylthiolation of Terminal Alkynes with CF3SiMe3 and Elemental Sulfur

   Chao Chen, Lingling Chu and Feng-Ling Qing*

   J. Am. Chem. Soc. 2012, 134, 1298-1304. DOI: 10.1021/ja305801m

 

12-13: Palladium-catalyzed direct α-arylation of α-fluoroketones: A straightforward route to α-fluoro-α-arylketones

   Chen Guo, Ruo-Wen Wang, Yong Guo and Feng-Ling Qing*

   J. Fluorine Chem. 2012, 133, 86-96. DOI: 10.1016/j.jfluchem.2011.08.004  

12-12: Coupling of sterically hindered aldehyde with fluorinated synthons: Stereoselective synthesis of fluorinated analogues of salinosporamide A

   Zeng-Hao Chen, Bing-Ling Wang etc. and Feng-Ling Qing*

   J. Fluorine Chem. 2012, 136, 12-19. DOI: 10.1016/j.jfluchem.2012.01.003

12-11: Palladium catalyzed direct α-arylation of α,α-difluoroketones with aryl bromides

   Chen Guo, Ruo-Wen Wang and Feng-Ling Qing*

   J. Fluorine Chem. 2012, 143, 135-142. DOI: 10.1016/j.jfluchem.2012.05.001

12-10: A Copper-Catalyzed Oxidative Trifluoromethylation of Terminal Alkynes and Aryl Boronic Acids Using (Trifluoromethyl)trimethylsilane

   Xueliang Jiang, Lingling Chu and Feng-Ling Qing*

   J. Org. Chem. 2012, 77, 1251-1257. DOI: 10.1021/jo202566h

 

12-9: Sequential Electrophilic Trifluoromethanesulfanylation−Cyclization of Tryptamine Derivatives: Synthesis of C(3)-Trifluoromethanesulfanylated Hexahydropyrrolo[2,3‑b]indoles

   Yi Yang, Xueliang Jiang and Feng-Ling Qing*

   J. Org. Chem. 2012, 77, 7538-7547. DOI: 10.1021/jo3013385

 

12-8: A Regio- and Diastereoselective Nickel-Catalyzed Allylation of Aromatic Aldehydes with α‑Halo-β,β-difluoropropene Derivatives

   Xiaowei Lin, Feng Zheng and Feng-Ling Qing*

   J. Org. Chem. 2012, 77, 8696-8704. DOI: 10.1021/jo301688d

 

12-7: A Copper-Catalyzed Oxidative Trifluoromethylation of Terminal Alkenes Using Nucleophilic CF3SiMe3: Efficient C(sp3)-CF3 Bond Formation

   Lingling Chu and Feng-Ling Qing*

   Org. Lett. 201214, 2106-2109. DOI: 10.1021/ol300639a 

12-6: Copper-Mediated Oxidative Cross-Coupling Reaction of Terminal Alkynes with α-Silyldifluoromethylphosphonates: An Efficient Method for α,α-Difluoropropargylphosphonates

   Xueliang Jiang, Lingling Chu and Feng-Ling Qing* 

   Org. Lett. 201214, 2870-2873. DOI: 10.1021/ol301113v 

12-5: Iron-Catalyzed Cross-Coupling Reactions between Arylzinc Reagents and Alkyl Halides Bearing β-Fluorines

   Xiaowei Lin, Feng Zheng and Feng-Ling Qing* 

   Organometallics 2012, 31, 1578-1582. DOI: 10.1021/om2005904

12-4: Copper-Catalyzed Aerobic Oxidative Trifluoromethylation of H-Phosphonates Using Trimethyl(trifluoromethyl)silane

   Lingling Chu and Feng-Ling Qing* 

   Synthesis 201244, 1521-1525. DOI: 10.1055/s-0031-1290806

12-3: Asymmetric synthesis of β-aryl-β-trifluoromethyl-β-aminoarones via Mannich-type reactions of ketone enolates with chiral aryl CF3-substituted N-tert-butanesulfinyl ketimines

   Yingle Liu, Yangen Huang and Feng-Ling Qing* 

   Tetrahedron 2012, 68, 4955-4961. DOI: 10.1016/j.tet.2012.04.070 

 12-2: Synthesis and biological evaluation of SGLT2 inhibitors: gem-difluoromethylenated Dapagliflozin analogs

   Zeng-Hao Chen, Ruo-Wen Wang and Feng-Ling Qing* 

   Tetrahedron Lett. 201253, 2171-2176. DOI: 10.1016/j.tetlet.2012.02.062

12-1: Synthesis of fluoroalkylated allylic amine derivatives via palladium-catalyzed Overman rearrangement

   Xin-Yi Jiang, Lingling Chu, Ruo-Wen Wang and Feng-Ling Qing* 

   Tetrahedron Lett. 201253, 6853-6857. DOI: 10.1016/j.tetlet.2012.10.045

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